When performing laser hair removal (LHR), which chromophore is primarily targeted?

In laser hair removal, the primary chromophore targeted is melanin in the skin. Melanin is the pigment responsible for the color of hair and skin, and it absorbs the energy produced by the laser. When the laser is used, it emits specific wavelengths of light that are effectively absorbed by the melanin in each hair follicle, leading to localized heating and destruction of the hair follicle without damaging the surrounding skin.

The efficacy of laser hair removal relies on the contrast between the color of the hair (dark hair has more melanin) and the color of the skin (lighter skin has less melanin), which allows for optimal targeting and minimizes the risk of skin damage. This principle is fundamental for the success of the procedure, making melanin the key target chromophore.

In contrast, other options like oxygen, hemoglobin, and collagen are not the primary targets for laser hair removal. While hemoglobin in blood is relevant for other laser treatments targeting vascular issues, and collagen may be involved in skin rejuvenation treatments, they do not play a significant role in the effectiveness of laser hair removal.